The same Entity Data Model can work with databases from different vendors. For example, one customer of your application might use SQL Server, while another customer might want Oracle.
Note: this topic is different than connecting to multiple database instances simultaneously ... which is also supported by DevForce.
The process to do this is not trivial, but it is doable. First, the database types must be close enough that the mapping file (the MSL) can map the CSDL to the SSDL for each database. Then you just need to specify the correct MSL and SSDL for each deployment. (See Entity Data Model XML for an overview of these files.)
To be more specific, the process looks like this:
This page discusses the metadata files and some options on how to deploy them:
http://blog.ondrejsv.com/post/Entity-Framework-metadata-deployment.aspx